This article is based on a qualitative anthropological research, conducted among the OPH (Organisations de Personnes Handicapées) of Western Senegal. The aim is to investigate the socio-cultural factors which influence the processes of social inclusion or self-determination of disabled people. By alternating the plan of cultural interpretation of disabilities and that of governance (connected to national protocols and international CRPD), a dialectic is established between urban and rural areas. Therapeutic pluralism, social stigma and microeconomic elements intersect in a complex system, in which the application of the conventions is about to perish. In this case the OPHs represent a possible solution which allows to build a network or even better a communitas that could support the diffusion of the CRPD’s principles.